Thomas-Tikhonenko Laboratory

Thomas-Tikhonenko Publications


  1. X.Y.Zhang, H.Pfeiffer, H.Mellert, T.Stanek, R.Sussman, A.Kumari, D.Yu, I.Rigoutsos, A.Thomas-Tikhonenko, H.Seidel, L.Chodosh, G.Packham, R.Baserga, S.McMahon: Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC. Mol Cell Biol in press 2012.
  2. P.Sundaram , S.Hultine, L.M.Smith, M.Dews, J.L.Fox, D.Biyashev, J.M.Schelter, Q.Huang, M.A.Cleary, O.V.Volpert, A.Thomas-Tikhonenko : p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers. Cancer Res 71(24), Dec 2011.
  3. E.Sotillo and A.Thomas-Tikhonenko: The long reach of non-coding RNAs. Nature Genet 43(7): 616-617, July 2011 Notes: Nature Genetics TOP CONTENT, July 2011.
  4. E.Sotillo-Pineiro and A.Thomas-Tikhonenko: Shielding the messenger (RNA): microRNA-based anticancer therapies. Pharmacology & Therapeutics 131(1): 18–32, July 2011 Notes: P&T TOP 25 HOTTEST ARTICLES April to June 2011.
  5. E.Sotillo, T.Laver, H.Mellert, J.M.Schelter, M.A.Cleary, S.McMahon, A.Thomas-Tikhonenko: Myc overexpression brings out unexpected anti-apoptotic effects of miR-34a. Oncogene 30(22): 2587–2594, June 2011 Notes: Oncogene TOP TEN list, June 2011.
  6. M.Dews, J.Fox, S.Hultine, P.Sundaram, W.Wang, Y.Y.Liu, E.Furth, G.H.Enders, W.El-Deiry, J.M.Schelter, M.A.Cleary, A.Thomas-Tikhonenko : Myc - miR-17~92 axis blunts TGFβ signaling and production of multiple TGFβ-dependent anti-angiogenic factors. Cancer Res 70(20): 8233-8246, Oct 2010.
  7. P.Mestdagh, A.K.Boström, F.Impens, E.Fredlund, G.Van Peer, P.De Antonellis, K. von Stedingk, B.Ghesquière, S.Schulte, M.Dews, A.Thomas-Tikhonenko, J.H. Schulte, M.Zollo, A.Schramm, K.Gevaert, H.Axelson, F.Speleman, and J.Vandesompele: Protein profiling identifies miR-17-92 as a master regulator of TGFβ-pathway activity in neuroblastoma. Mol Cell 40(5): 762–773, Dec 2010.
  8. T.C.Chang, L.R.Zeitels, H.W.Hwang, E.A.Wentzel, M.Dews, J.Jung, P.Gao, C.V.Dang, M.A.Beer, A.Thomas-Tikhonenko, J.T.Mendell: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci USA 106(9): 3384–3389, Mar 2009.
  9. O.Chayka, D.Corvetta, M.Dews, A.E.Caccamo, I.Piotrowska, G.Santilli, S.Gibson, N.J.Sebire, N.Himoudi, M.D.Hogarty, J.Anderson, S.Bettuzzi, A.Thomas-Tikhonenko, A.Sala: Clusterin, a haploinsufficient tumour suppressor gene in neuroblastomas. J Natl Cancer Inst 101(9): 663-677, May 2009.
  10. T.C.Chang, D.Yu, Y.S.Lee, E.A.Wentzel, D.E.Arking, K.M.West, C.V.Dang, A.Thomas-Tikhonenko, J.T.Mendell: Widespread microRNA repression by Myc contributes to tumorigenesis. Nature Genet 40(1): 43-50, Jan 2008.