Naomi Balamuth, MD

Attending physician

Assistant professor

Contact Naomi Balamuth, MD


Specialties and Services


Yale University, New Haven, CT

Columbia University, NY


The Children's Hospital of Philadelphia, Pa.


The Children's Hospital of Philadelphia, Pa.


The Children's Hospital of Philadelphia, Pa.

Board Certification

American Board of Pediatrics

American Board of Pediatrics/Pediatric Hematology-Oncology

Year Appointed


Extended Bio

My area of interest is in pediatric sarcomas, a subset of solid tumors. The majority of my time is spent in clinical care and improving our global approach to sarcomas. I am working on building up the sarcoma program at The Children's Hospital of Philadelphia to ensure we have a team approach to these complicated tumors in children, and to integrate the best new and established treatments for these patients.

At Children's Hospital, we are first and foremost a family care center. I work to educate families and patients to understand the diagnosis and treatment plan so everyone is on the same page. I talk to families about the process and have them participate in the child's care. I also include the child in the discussion, in an age appropriate manner.

We are creating a team structure at Children's Hospital to bring innovative treatment to our patients. Our sarcoma physicians and researchers meet frequently to ensure that each patient is receiving the latest and best treatment protocols. We also have hired our first nurse practitioner, who specializes in sarcomas.

I am the institutional principle investigator for a high risk rhabdomyosarcoma study for tumors in patients with a poor prognosis. Rhabdomyosarcoma is a fast-growing, highly malignant tumor responsible for more than half of the soft tissue sarcomas in children. We are looking at the clinical outcomes of the last, best therapy with the addition of two novel drugs. One of our goals is to bring more studies for sarcoma patients to Children's Hospital.

Children's Hospital has the unique capacity to take care of complicated patients with sarcomas. We have outstanding clinical care and a close relationship with our colleagues who are advancing our understanding and treatment of these challenging tumors.




Kazak, A. E., Alderfer, M.A., & Rodriguez, A. (2008). Psychological issues in cancer survival in pediatric populations. In S. Miller, D. Bowen, R. Croyle, & J. Rowland (Eds.) Handbook of Behavioral Science and Cancer. pp.449-465. Washington, DC: American Psychological Association.

Pentz, R.D., Haight, A.E., Noll, R.B., Barfield, R., Pelletier, W., Davies, S., Alderfer, M.A., & Hinds, P. (2008). The ethical justification for a minor sibling bone marrow donation: A case
study. The Oncologist, 13, 148-151.

Original Papers

Balamuth NJ, Womer RB. Ewing's sarcoma. Lancet Oncol. 2010 Feb;11(2):184-92. Review. Read abstract

Balamuth NJ, Wood A, Wang Q, Jagannathan J, Mayes P, Zhang Z, Chen Z, Rappaport E, Courtright J, Pawel B, Weber B, Wooster R, Sekyere EO, Marshall GM, Maris JM. Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target. Cancer Res. 2010 Apr 1;70(7):2749-58. Epub 2010 Mar 16. Read abstract

Balamuth N, Nichols KE, Paessler M, Teachey DT. Use of rituximab in conjuction with immunosuppressive chemotherapy as a novel therapy for Epstein Barr virus-associated hemophagoytic lymphohistiocytosis. J Pediatr Hematol Oncol 2007. 29(8):569-73. Read abstract