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Peter C. Phillips, MD

Peter C. Phillips, MD

Director, Pediatric Neuro-oncology Program

Attending physician

Professor of Pediatrics, University of Pennsylvania School of Medicine

Contact Peter C. Phillips, MD

Resume

  • Department: Pediatrics
  • Division: Neurology
  • Primary Address:
    HUP
    3400 SPRUCE ST.
    4283
    Philadelphia, PA 19104
  • 215-590-2107

    Expertise

    Pediatric Neuro-Oncology experimental therapeutics

    Appointments

    • Professor of Pediatrics, University of Pennsylvania School of Medicine (2000 – present)
    • Professor of Neurology at the Children's Hospital of Philadelphia (2000 – present)
    • Associate Professor of Pediatrics, University of Pennsylvania School of Medicine (1995 – 2000)
    • Associate Professor of Neurology at the Children's Hospital of Philadelphia (1995 – 2000)
    • Assistant Professor of Pediatrics, University of Pennsylvania School of Medicine (1991 – 1995)
    • Assistant Professor of Neurology, University of Pennsylvania School of Medicine (1991 – 1995)

    Education

    • M.D., University of Connecticut School of Medicine (1978)
    • B.A., Philosophy, Oberlin College (1974)

    Extended Bio

    Specialties and Services

    Practice Locations

    Education

    University of Connecticut School of Medicine, Farmington, Conn.

    Internship

    Memorial Sloan-Kettering Cancer Center,NY

    Residency

    New York Hospital, NY Neurological Institute of New York, NY

    Fellowship

    Children's Hospital, Boston, Mass.

    Board Certification

    American Board of Pediatrics
    American Board of Psychiatry and Neurology/Child Neurology

    Year Appointed

    1991

    Special Interests

    Research in neuro-oncology and cellular mechanisms of neurotoxicity

    Research Interests

    Stokes research summary

    Publications

    • Pavlakis S G, Phillips P C, DiMauro S, De Vivo D C, Rowland L P. Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: a distinctive clinical syndrome.. Annals of neurology. Vol 16(4) . 1984 Oct:481-8.
    • Phillips P C, Kremzner L T, De Vivo D C. Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors.. Annals of neurology. Vol 19(4) . 1986 Apr:360-4.
    • Phillips P C, Thaler H T, Berger C A, Fleisher M, Wellner D, Allen J C, Rottenberg D A. Acute high-dose methotrexate neurotoxicity in the rat.. Annals of neurology. Vol 20(5) . 1986 Nov:583-9.
    • Phillips P C, Dhawan V, Strother S C, Sidtis J J, Evans A C, Allen J C, Rottenberg D A. Reduced cerebral glucose metabolism and increased brain capillary permeability following high-dose methotrexate chemotherapy: a positron emission tomographic study.. Annals of neurology. Vol 21(1) . 1987 Jan:59-63.
    • Phillips P C, Lorentsen K J, Shropshire L C, Ahn H S. Congenital odontoid aplasia and posterior circulation stroke in childhood.. Annals of neurology. Vol 23(4) . 1988 Apr:410-3.
    • Phillips P C, Thaler H T, Allen J C, Rottenberg D A. High-dose leucovorin reverses acute high-dose methotrexate neurotoxicity in the rat.. Annals of neurology. Vol 25(4) . 1989 Apr:365-72.
    • O'Tuama L A, Phillips P C, Strauss L C, Carson B C, Uno Y, Smith Q R, Dannals R F, Wilson A A, Ravert H T, Loats S. Two-phase [11C]L-methionine PET in childhood brain tumors.. Pediatric neurology. Vol 6(3) . 1990 May-Jun:163-70.
    • Blews D E, Wang H, Kumar A J, Robb P A, Phillips P C, Bryan R N. Intradural spinal metastases in pediatric patients with primary intracranial neoplasms: Gd-DTPA enhanced MR vs CT myelography.. Journal of computer assisted tomography. Vol 14(5) . 1990 Sep-Oct:730-5.
    • Longee D C, Friedman H S, Phillips P C, Burger P C, Oakes W J, Heffez D, Wharam M, Strauss L, Fuller G N, Schold S C. Osteoblastic metastases from astrocytomas: a report of two cases.. Medical and pediatric oncology. Vol 19(4) . 1991:318-24.
    • O'Tuama L A, Phillips P C, Smith Q R, Uno Y, Dannals R F, Wilson A A, Ravert H T, Loats S, Loats H A, Wagner H N. L-methionine uptake by human cerebral cortex: maturation from infancy to old age.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. Vol 32(1) . 1991 Jan:16-22.
    • Phillips P C, Moeller J R, Sidtis J J, Dhawan V, Steinherz P G, Strother S C, Ginos J Z, Rottenberg D A. Abnormal cerebral glucose metabolism in long-term survivors of childhood acute lymphocytic leukemia.. Annals of neurology. Vol 29(3) . 1991 Mar:263-71.
    • Phillips P C. Antineoplastic drug resistance in brain tumors.. Neurologic clinics. Vol 9(2) . 1991 May:383-404.
    • Bruggers C S, Friedman H S, Phillips P C, Wiener M D, Hockenberger B, Oakes W J, Buckley E G. Leptomeningeal dissemination of optic pathway gliomas in three children.. American journal of ophthalmology. Vol 111(6) . 1991 Jun:719-23.
    • Corden B J, Strauss L C, Killmond T, Carson B S, Wharam M D, Kumar A J, Piantadosi S, Robb P A, Phillips P C. Cisplatin, ara-C and etoposide (PAE) in the treatment of recurrent childhood brain tumors.. Journal of neuro-oncology. Vol 11(1) . 1991 Aug:57-63.
    • Nabors M W, Griffin C A, Zehnbauer B A, Hruban R H, Phillips P C, Grossman S A, Brem H, Colvin O M. Multidrug resistance gene (MDR1) expression in human brain tumors.. Journal of neurosurgery. Vol 75(6) . 1991 Dec:941-6.
    • O'Tuama L A, Phillips P C. PET imaging of brain tumors.. Annals of neurology. Vol 30(6) . 1991 Dec:851.
    • Tsuchida T, Hruban R H, Carson B S, Phillips P C. Colloid cysts of the third ventricle: immunohistochemical evidence for nonneuroepithelial differentiation.. Human pathology. Vol 23(7) . 1992 Jul:811-6.
    • Phillips P C, Than T T, Cork L C, Hilton J, Carson B S, Colvin O M, Grochow L B. Intrathecal 4-hydroperoxycyclophosphamide: neurotoxicity, cerebrospinal fluid pharmacokinetics, and antitumor activity in a rabbit model of VX2 leptomeningeal carcinomatosis.. Cancer research. Vol 52(22) . 1992 Nov:6168-74.
    • Tsuchida T, Hruban R H, Carson B S, Phillips P C. Folliculo-stellate cells in the human anterior pituitary express cytokeratin.. Pathology, research and practice. Vol 189(2) . 1993 Mar:184-8.
    • Resar L M, Phillips P C, Kastan M B, Leventhal B G, Bowman P W, Civin C I. Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of B-cell type.. Cancer. Vol 71(1) . 1993 Jan:117-23.
    • Phillips P C, Levow C, Catterall M, Colvin O M, Pastan I, Brem H. Transforming growth factor-alpha-Pseudomonas exotoxin fusion protein (TGF-alpha-PE38) treatment of subcutaneous and intracranial human glioma and medulloblastoma xenografts in athymic mice.. Cancer research. Vol 54(4) . 1994 Feb:1008-15.
    • Radcliffe J, Bunin G R, Sutton L N, Goldwein J W, Phillips P C. Cognitive deficits in long-term survivors of childhood medulloblastoma and other noncortical tumors: age-dependent effects of whole brain radiation.. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. Vol 12(4) . 1994 Jun:327-34.
    • Torres C F, Rebsamen S, Silber J H, Sutton L N, Bilaniuk L T, Zimmerman R A, Goldwein J W, Phillips P C, Lange B J. Surveillance scanning of children with medulloblastoma.. The New England journal of medicine. Vol 330(13) . 1994 Mar:892-5.
    • Yu I T, Griffin C A, Phillips P C, Strauss L C, Perlman E J. Numerical sex chromosomal abnormalities in pineal teratomas by cytogenetic analysis and fluorescence in situ hybridization.. Laboratory investigation; a journal of technical methods and pathology. Vol 72(4) . 1995 Apr:419-23.
    • Jones S M, Phillips P C, Molloy P T, Lange B J, Needle M N, Biegel J A. Congenital anomalies and genetic disorders in families of children with central nervous system tumours.. Journal of medical genetics. Vol 32(8) . 1995 Aug:627-32.
    • Jones S M, Phillips P C, Molloy P T, Lange B J, Needle M N, Bunin G R, Biegel J A. Neurologic and other disorders in relatives of pediatric patients with CNS tumors.. Pediatric neurology. Vol 13(2) . 1995 Sep:111-6.
    • Molloy P T, Bilaniuk L T, Vaughan S N, Needle M N, Liu G T, Zackai E H, Phillips P C. Brainstem tumors in patients with neurofibromatosis type 1: a distinct clinical entity.. Neurology. Vol 45(10) . 1995 Oct:1897-902.
    • Phillips P C. Neuro-oncology: clinical research and applied technology in the mid-1990s.. Current opinion in neurology. Vol 8(6) . 1995 Dec:411-3.
    • Felix C A, Slavc I, Dunn M, Strauss E A, Phillips P C, Rorke L B, Sutton L, Bunin G R, Biegel J A. p53 gene mutations in pediatric brain tumors.. Medical and pediatric oncology. Vol 25(6) . 1995 Dec:431-6.
    • Janss A J, Yachnis A T, Silber J H, Trojanowski J Q, Lee V M, Sutton L N, Perilongo G, Rorke L B, Phillips P C. Glial differentiation predicts poor clinical outcome in primitive neuroectodermal brain tumors.. Annals of neurology. Vol 39(4) . 1996 Apr:481-9.
    • Liu G T, Galetta S L, Rorke L B, Bilaniuk L T, Vojta D D, Molloy P T, Phillips P C, Needle M, Duhaime A C, Sutton L N, Volpe N J. Gangliogliomas involving the optic chiasm.. Neurology. Vol 46(6) . 1996 Jun:1669-73.
    • Phillips P C. Waiting for a compensatory mutation: phase zero of the shifting-balance process.. Genetical research. Vol 67(3) . 1996 Jun:271-83.
    • Sutton L N, Phillips P C, Molloy P T. Surgical management of medulloblastoma.. Journal of neuro-oncology. Vol 29(1) . 1996 Jul:9-21.
    • Eck S L, Alavi J B, Alavi A, Davis A, Hackney D, Judy K, Mollman J, Phillips P C, Wheeldon E B, Wilson J M. Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: a phase I trial.. Human gene therapy. Vol 7(12) . 1996 Aug:1465-82.
    • Blaney S M, Phillips P C, Packer R J, Heideman R L, Berg S L, Adamson P C, Allen J C, Sallan S E, Jakacki R I, Lange B J, Reaman G H, Horowitz M E, Poplack D G, Balis F M. Phase II evaluation of topotecan for pediatric central nervous system tumors.. Cancer. Vol 78(3) . 1996 Aug:527-31.
    • Radcliffe J, Bennett D, Kazak A E, Foley B, Phillips P C. Adjustment in childhood brain tumor survival: child, mother, and teacher report.. Journal of pediatric psychology. Vol 21(4) . 1996 Aug:529-39.
    • Molloy P T, Yachnis A T, Rorke L B, Dattilo J J, Needle M N, Millar W S, Goldwein J W, Sutton L N, Phillips P C. Central nervous system medulloepithelioma: a series of eight cases including two arising in the pons.. Journal of neurosurgery. Vol 84(3) . 1996 Mar:430-6.
    • Johnson J H, Phillips P C. Malignant gliomas in children.. Cancer investigation. Vol 14(6) . 1996:609-21.
    • Johnson J H, Hariharan S, Berman J, Sutton L N, Rorke L B, Molloy P, Phillips P C. Clinical outcome of pediatric gangliogliomas: ninety-nine cases over 20 years.. Pediatric neurosurgery. Vol 27(4) . 1997 Oct:203-7.
    • Tóth Z, Gintner Z, Bánóczy J, Phillips P C. The effect of fluoridated milk on human dental enamel in an in vitro demineralization model.. Caries research. Vol 31(3) . 1997:212-5.
    • Biegel J A, Janss A J, Raffel C, Sutton L, Rorke L B, Harper J M, Phillips P C. Prognostic significance of chromosome 17p deletions in childhood primitive neuroectodermal tumors (medulloblastomas) of the central nervous system.. Clinical cancer research : an official journal of the American Association for Cancer Research. Vol 3(3) . 1997 Mar:473-8.
    • Needle M N, Molloy P T, Geyer J R, Herman-Liu A, Belasco J B, Goldwein J W, Sutton L, Phillips P C. Phase II study of daily oral etoposide in children with recurrent brain tumors and other solid tumors.. Medical and pediatric oncology. Vol 29(1) . 1997 Jul:28-32.
    • Needle M N, Goldwein J W, Grass J, Cnaan A, Bergman I, Molloy P, Sutton L, Zhao H, Garvin J H, Phillips P C. Adjuvant chemotherapy for the treatment of intracranial ependymoma of childhood.. Cancer. Vol 80(2) . 1997 Jul:341-7.
    • Sutton L N, Wang Z J, Wehrli S L, Marwaha S, Molloy P, Phillips P C, Zimmerman R A. Proton spectroscopy of suprasellar tumors in pediatric patients.. Neurosurgery. Vol 41(2) . 1997 Aug:388-94; discussion 394-5.
    • Bilaniuk L T, Molloy P T, Zimmerman R A, Phillips P C, Vaughan S N, Liu G T, Sutton L N, Needle M. Neurofibromatosis type 1: brain stem tumours.. Neuroradiology. Vol 39(9) . 1997 Sep:642-53.
    • Phillips P C. The rise and fall of new mutations.. Trends in ecology & evolution. Vol 12(12) . 1997 Dec:466-8.
    • Needle M N, Cnaan A, Dattilo J, Chatten J, Phillips P C, Shochat S, Sutton L N, Vaughan S N, Zackai E H, Zhao H, Molloy P T. Prognostic signs in the surgical management of plexiform neurofibroma: the Children's Hospital of Philadelphia experience, 1974-1994.. The Journal of pediatrics. Vol 131(5) . 1997 Nov:678-82.
    • Stragliotto G, Packer R J, Rausen A R, Coccia P F, Meadows A T, Phillips P C, Finlay J L. "Outcome of post-radiation secondary glioblastoma in children".. Medical and pediatric oncology. Vol 30(3) . 1998 Mar:194-5.
    • Liu G T, Phillips P C, Molloy P T, Needle M N, Galetta S L, Balcer L J, Schut L, Duhaime A C, Sutton L N. Visual impairment associated with mutism after posterior fossa surgery in children.. Neurosurgery. Vol 42(2) . 1998 Feb:253-6; discussion 256-7.
    • Girard N, Wang Z J, Erbetta A, Sutton L N, Phillips P C, Rorke L B, Zimmerman R A. Prognostic value of proton MR spectroscopy of cerebral hemisphere tumors in children.. Neuroradiology. Vol 40(2) . 1998 Feb:121-5.
    • Schanzer B, Bordaberry M, Jeffery A R, McNeil D E, Phillips P C. The child with divergence paresis.. Survey of ophthalmology. Vol 42(6) . 1998 May-Jun:571-6.
    • Tang Y, Marwaha S, Rutkowski J L, Tennekoon G I, Phillips P C, Field J. A role for Pak protein kinases in Schwann cell transformation.. Proceedings of the National Academy of Sciences of the United States of America. Vol 95(9) . 1998 Apr:5139-44.
    • Phillips P C. The language of gene interaction.. Genetics. Vol 149(3) . 1998 Jul:1167-71.
    • Fisher P G, Needle M N, Cnaan A, Zhao H, Geyer J R, Molloy P T, Goldwein J W, Herman-Liu A B, Phillips P C. Salvage therapy after postoperative chemotherapy for primary brain tumors in infants and very young children.. Cancer. Vol 83(3) . 1998 Aug:566-74.
    • Janss A J, Levow C, Bernhard E J, Muschel R J, McKenna W G, Sutton L, Phillips P C. Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines.. Experimental cell research. Vol 243(1) . 1998 Aug:29-38.
    • Phillips P C, Johnson N A. The population genetics of synthetic lethals.. Genetics. Vol 150(1) . 1998 Sep:449-58.
    • Janss A J, Cnaan A, Zhao H, Shpilsky A, Levow C, Sutton L, Phillips P C. Synergistic cytotoxicity of topoisomerase I inhibitors with alkylating agents and etoposide in human brain tumor cell lines.. Anti-cancer drugs. Vol 9(7) . 1998 Aug:641-52.
    • Phillips P C. From complex traits to complex alleles.. Trends in genetics : TIG. Vol 15(1) . 1999 Jan:6-8.
    • Patti R, Reddy C D, Geoerger B, Grotzer M A, Raghunath M, Sutton L N, Phillips P C. Autocrine secreted insulin-like growth factor-I stimulates MAP kinase-dependent mitogenic effects in human primitive neuroectodermal tumor/medulloblastoma.. International journal of oncology. Vol 16(3) . 2000 Mar:577-84.
    • Grotzer M A, Janss A J, Fung K, Biegel J A, Sutton L N, Rorke L B, Zhao H, Cnaan A, Phillips P C, Lee V M, Trojanowski J Q. TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Vol 18(5) . 2000 Mar:1027-35.
    • Armstrong C L, Corn B W, Ruffer J E, Pruitt A A, Mollman J E, Phillips P C. Radiotherapeutic effects on brain function: double dissociation of memory systems.. Neuropsychiatry, neuropsychology, and behavioral neurology. Vol 13(2) . 2000 Apr:101-11.
    • Reddy A T, Janss A J, Phillips P C, Weiss H L, Packer R J. Outcome for children with supratentorial primitive neuroectodermal tumors treated with surgery, radiation, and chemotherapy.. Cancer. Vol 88(9) . 2000 May:2189-93.
    • Raghunath M, Patti R, Bannerman P, Lee C M, Baker S, Sutton L N, Phillips P C, Damodar Reddy C. A novel kinase, AATYK induces and promotes neuronal differentiation in a human neuroblastoma (SH-SY5Y) cell line.. Brain research. Molecular brain research. Vol 77(2) . 2000 May:151-62.
    • Grotzer M A, Patti R, Geoerger B, Eggert A, Chou T T, Phillips P C. Biological stability of RNA isolated from RNAlater-treated brain tumor and neuroblastoma xenografts.. Medical and pediatric oncology. Vol 34(6) . 2000 Jun:438-42.
    • Whitlock MC, Phillips PC. The exquisite corpse: a shifting view of the shifting balance.. Trends in ecology & evolution. Vol 15(9) . 2000 Sep:347-348.
    • Grotzer M A, Janss A J, Phillips P C, Trojanowski J Q. Neurotrophin receptor TrkC predicts good clinical outcome in medulloblastoma and other primitive neuroectodermal brain tumors.. Klinische Pädiatrie. Vol 212(4) . 2000 Jul-Aug:196-9.
    • Grotzer M A, Eggert A, Zuzak T J, Janss A J, Marwaha S, Wiewrodt B R, Ikegaki N, Brodeur G M, Phillips P C. Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.. Oncogene. Vol 19(40) . 2000 Sep:4604-10.
    • Geoerger B, Tang C B, Cesano A, Visonneau S, Marwaha S, Judy K D, Sutton L N, Santoli D, Phillips P C. Antitumor activity of a human cytotoxic T-cell line (TALL-104) in brain tumor xenografts.. Neuro-oncology. Vol 2(2) . 2000 Apr:103-13.
    • Janss A J, Maity A, Tang C B, Muschel R J, McKenna W G, Sutton L, Phillips P C. Decreased cyclin B1 expression contributes to G2 delay in human brain tumor cells after treatment with camptothecin.. Neuro-oncology. Vol 3(1) . 2001 Jan:11-21.
    • Grotzer M A, Hogarty M D, Janss A J, Liu X, Zhao H, Eggert A, Sutton L N, Rorke L B, Brodeur G M, Phillips P C. MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma.. Clinical cancer research : an official journal of the American Association for Cancer Research. Vol 7(8) . 2001 Aug:2425-33.
    • Phillips P C, Whitlock M C, Fowler K. Inbreeding changes the shape of the genetic covariance matrix in Drosophila melanogaster.. Genetics. Vol 158(3) . 2001 Jul:1137-45.
    • Grotzer M A, Geoerger B, Janss A J, Zhao H, Rorke L B, Phillips P C. Prognostic significance of Ki-67 (MIB-1) proliferation index in childhood primitive neuroectodermal tumors of the central nervous system.. Medical and pediatric oncology. Vol 36(2) . 2001 Feb:268-73.
    • Grotzer M A, Wiewrodt R, Janss A J, Zhao H, Cnaan A, Sutton L N, Rorke L B, Phillips P C. High microvessel density in primitive neuroectodermal brain tumors of childhood.. Neuropediatrics. Vol 32(2) . 2001 Apr:75-9.
    • Huber H, Eggert A, Janss A J, Wiewrodt R, Zhao H, Sutton L N, Rorke L B, Phillips P C, Grotzer M A. Angiogenic profile of childhood primitive neuroectodermal brain tumours/medulloblastomas.. European journal of cancer (Oxford, England : 1990). Vol 37(16) . 2001 Nov:2064-72.
    • Damodar Reddy C, Marwaha S, Patti R, Raghunath M, Duhaime A C, Sutton L, Phillips P C. Role of MAP kinase pathways in primitive neuroectodermal tumors.. Anticancer research. Vol 21(4A) . 2001 Jul-Aug:2733-8.
    • Grotzer M A, Janss A J, Fung K M, Sutton L N, Zhao H, Trojanowski J Q, Rorke L B, Phillips P C. Abundance of apoptotic neoplastic cells in diagnostic biopsy samples is not a prognostic factor in childhood primitive neuroectodermal tumors of the central nervous system.. Journal of pediatric hematology/oncology. Vol 23(1) . 2001 Jan:25-9.
    • Geoerger B, Kerr K, Tang C B, Fung K M, Powell B, Sutton L N, Phillips P C, Janss A J. Antitumor activity of the rapamycin analog CCI-779 in human primitive neuroectodermal tumor/medulloblastoma models as single agent and in combination chemotherapy.. Cancer research. Vol 61(4) . 2001 Feb:1527-32.
    • Balcer L J, Liu G T, Heller G, Bilaniuk L, Volpe N J, Galetta S L, Molloy P T, Phillips P C, Janss A J, Vaughn S, Maguire M G. Visual loss in children with neurofibromatosis type 1 and optic pathway gliomas: relation to tumor location by magnetic resonance imaging.. American journal of ophthalmology. Vol 131(4) . 2001 Apr:442-5.
    • Carey M E, Barakat L P, Foley B, Gyato K, Phillips P C. Neuropsychological functioning and social functioning of survivors of pediatric brain tumors: evidence of nonverbal learning disability.. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. Vol 7(4) . 2001 Dec:265-72.
    • Zuzak T J, Steinhoff D F, Sutton L N, Phillips P C, Eggert A, Grotzer M A. Loss of caspase-8 mRNA expression is common in childhood primitive neuroectodermal brain tumour/medulloblastoma.. European journal of cancer (Oxford, England : 1990). Vol 38(1) . 2002 Jan:83-91.
    • Stewart Andrew D, Phillips Patrick C. Selection and maintenance of androdioecy in Caenorhabditis elegans.. Genetics. Vol 160(3) . 2002 Mar:975-82.
    • Patti Ratnakar, Gumired Kiranmai, Reddanna Pallu, Sutton Leslie N, Phillips Peter C, Reddy C Damodar. Overexpression of cyclooxygenase-2 (COX-2) in human primitive neuroectodermal tumors: effect of celecoxib and rofecoxib.. Cancer letters. Vol 180(1) . 2002 Jun:13-21.
    • Whitlock Michael C, Phillips Patrick C, Fowler Kevin. Persistence of changes in the genetic covariance matrix after a bottleneck.. Evolution; international journal of organic evolution. Vol 56(10) . 2002 Oct:1968-75.
    • Barakat Lamia P, Hetzke Jennifer D, Foley Bernadette, Carey Marissa E, Gyato Kunsang, Phillips Peter C. Evaluation of a social-skills training group intervention with children treated for brain tumors: a pilot study.. Journal of pediatric psychology. Vol 28(5) . 2003 Jul-Aug:299-307.
    • Gumireddy Kiranmai, Ikegaki Naohiko, Phillips Peter C, Sutton Leslie N, Reddy C Damodar. Effect of 20-epi-1alpha,25-dihydroxyvitamin D3 on the proliferation of human neuroblastoma: role of cell cycle regulators and the Myc-Id2 pathway.. Biochemical pharmacology. Vol 65(12) . 2003 Jun:1943-55.
    • Jovelin R, Ajie B C, Phillips P C. Molecular evolution and quantitative variation for chemosensory behaviour in the nematode genus Caenorhabditis.. Molecular ecology. Vol 12(5) . 2003 May:1325-37.
    • Gumireddy Kiranmai, Reddy G S, Ikegaki Naohiko, Binderup Lise, Sutton Leslie N, Phillips Peter C, Reddy C Damodar. Anti-proliferative effects of 20-epi-vitamin-D3 analogue, KH1060 in human neuroblastoma: induction of RAR-beta and p21(Cip1).. Cancer letters. Vol 190(1) . 2003 Feb:51-60.
    • Gupta A, Cohen B H, Ruggieri P, Packer R J, Phillips P C. Phase I study of thalidomide for the treatment of plexiform neurofibroma in neurofibromatosis 1.. Neurology. Vol 60(1) . 2003 Jan:130-2.
    • Gumireddy Kiranmai, Sutton Leslie N, Phillips Peter C, Reddy C Damodar. All-trans-retinoic acid-induced apoptosis in human medulloblastoma: activation of caspase-3/poly(ADP-ribose) polymerase 1 pathway.. Clinical cancer research : an official journal of the American Association for Cancer Research. Vol 9(11) . 2003 Sep:4052-9.
    • Pingoud-Meier Carmen, Lang Doris, Janss Anna J, Rorke Lucy B, Phillips Peter C, Shalaby Tarek, Grotzer Michael A. Loss of caspase-8 protein expression correlates with unfavorable survival outcome in childhood medulloblastoma.. Clinical cancer research : an official journal of the American Association for Cancer Research. Vol 9(17) . 2003 Dec:6401-9.
    • Stripp Diana C H, Maity Amit, Janss Anna J, Belasco Jean B, Tochner Zelig A, Goldwein Joel W, Moshang Thomas, Rorke Lucy B, Phillips Peter C, Sutton Leslie N, Shu Hui-Kuo G. Surgery with or without radiation therapy in the management of craniopharyngiomas in children and young adults.. International journal of radiation oncology, biology, physics. Vol 58(3) . 2004 Mar:714-20.
    • Maity Amit, Shu Hui-Kuo G, Janss Anna, Belasco Jean B, Rorke Lucy, Phillips Peter C, Sutton Leslie N, Goldwein Joel W. Craniospinal radiation in the treatment of biopsy-proven intracranial germinomas: twenty-five years' experience in a single center.. International journal of radiation oncology, biology, physics. Vol 58(4) . 2004 Mar:1165-70.
    • Liu Grant T, Brodsky Michael C, Phillips Peter C, Belasco Jean, Janss Anna, Golden Jeffrey C, Bilaniuk Larissa L, Burson G Timothy, Duhaime Ann-Christine, Sutton Leslie N. Optic radiation involvement in optic pathway gliomas in neurofibromatosis.. American journal of ophthalmology. Vol 137(3) . 2004 Mar:407-14.
    • McGuigan Katrina, Phillips Patrick C, Postlethwait John H. Evolution of sarcomeric myosin heavy chain genes: evidence from fish.. Molecular biology and evolution. Vol 21(6) . 2004 Jun:1042-56.
    • Estes Suzanne, Phillips Patrick C, Denver Dee R, Thomas W Kelley, Lynch Michael. Mutation accumulation in populations of varying size: the distribution of mutational effects for fitness correlates in Caenorhabditis elegans.. Genetics. Vol 166(3) . 2004 Mar:1269-79.
    • Hersch Erika I, Phillips Patrick C. Power and potential bias in field studies of natural selection.. Evolution; international journal of organic evolution. Vol 58(3) . 2004 Mar:479-85.
    • Bucci Mary Kara, Maity Amit, Janss Anna J, Belasco Jean B, Fisher Michael J, Tochner Zelig A, Rorke Lucy, Sutton Leslie N, Phillips Peter C, Shu Hui-Kuo G. Near complete surgical resection predicts a favorable outcome in pediatric patients with nonbrainstem, malignant gliomas: results from a single center in the magnetic resonance imaging era.. Cancer. Vol 101(4) . 2004 Aug:817-24.
    • Fisher Michael J, Lange Beverly J, Needle Michael N, Janss Anna J, Shu Hui-Kuo G, Adamson Peter C, Phillips Peter C. Amifostine for children with medulloblastoma treated with cisplatin-based chemotherapy.. Pediatric blood & cancer. Vol 43(7) . 2004 Dec:780-4.
    • Proulx Stephen R, Phillips Patrick C. The opportunity for canalization and the evolution of genetic networks.. The American naturalist. Vol 165(2) . 2005 Feb:147-62.
    • Kimmel Charles B, Ullmann Bonnie, Walker Charline, Wilson Catherine, Currey Mark, Phillips Patrick C, Bell Michael A, Postlethwait John H, Cresko William A. Evolution and development of facial bone morphology in threespine sticklebacks.. Proceedings of the National Academy of Sciences of the United States of America. Vol 102(16) . 2005 Apr:5791-6.
    • Aagaard Jan E, Olmstead Richard G, Willis John H, Phillips Patrick C. Duplication of floral regulatory genes in the Lamiales.. American journal of botany. Vol 92(8) . 2005 Aug:1284-93.
    • Phillips Patrick C. Testing hypotheses regarding the genetics of adaptation.. Genetica. Vol 123(1-2) . 2005 Feb:15-24.
    • Jovelin Richard, Phillips Patrick C. Functional constraint and divergence in the G protein family in Caenorhabditis elegans and Caenorhabditis briggsae.. Molecular genetics and genomics : MGG. Vol 273(4) . 2005 Jun:299-310.
    • Ajie Beverly C, Estes Suzanne, Lynch Michael, Phillips Patrick C. Behavioral degradation under mutation accumulation in Caenorhabditis elegans.. Genetics. Vol 170(2) . 2005 Jun:655-60.
    • Estes Suzanne, Ajie Beverly C, Lynch Michael, Phillips Patrick C. Spontaneous mutational correlations for life-history, morphological and behavioral characters in Caenorhabditis elegans.. Genetics. Vol 170(2) . 2005 Jun:645-53.
    • Proulx Stephen R, Promislow Daniel E L, Phillips Patrick C. Network thinking in ecology and evolution.. Trends in ecology & evolution. Vol 20(6) . 2005 Jun:345-53.
    • Estes Suzanne, Phillips Patrick C. Variation in pleiotropy and the mutational underpinnings of the G-matrix.. Evolution; international journal of organic evolution. Vol 60(12) . 2006 Dec:2655-60.
    • Teotónio Henrique, Manoel Diogo, Phillips Patrick C. Genetic variation for outcrossing among Caenorhabditis elegans isolates.. Evolution; international journal of organic evolution. Vol 60(6) . 2006 Jun:1300-5.
    • Nissim Itzhak, Horyn Oksana, Daikhin Yevgeny, Nissim Ilana, Luhovyy Bohdan, Phillips Peter C, Yudkoff Marc. Ifosfamide-induced nephrotoxicity: mechanism and prevention.. Cancer research. Vol 66(15) . 2006 Aug:7824-31.
    • Phillips Patrick C. One perfect worm.. Trends in genetics : TIG. Vol 22(8) . 2006 Aug:405-7.
    • Proulx Stephen R, Phillips Patrick C. Allelic divergence precedes and promotes gene duplication.. Evolution; international journal of organic evolution. Vol 60(5) . 2006 May:881-92.
    • Janzen F J, Phillips P C. Exploring the evolution of environmental sex determination, especially in reptiles.. Journal of evolutionary biology. Vol 19(6) . 2006 Nov:1775-84.
    • Aagaard Jan E, Willis John H, Phillips Patrick C. Relaxed selection among duplicate floral regulatory genes in Lamiales.. Journal of molecular evolution. Vol 63(4) . 2006 Oct:493-503.
    • Armstrong Gregory T, Phillips Peter C, Rorke-Adams Lucy B, Judkins Alexander R, Localio A Russell, Fisher Michael J. Gliomatosis cerebri: 20 years of experience at the Children's Hospital of Philadelphia.. Cancer. Vol 107(7) . 2006 Oct:1597-606.
    • Reddy C Damodar, Patti Ratnakar, Guttapalli Asha, Maris John M, Yanamandra Niranjan, Rachamallu Aparna, Sutton Leslie N, Phillips Peter C, Posner Gary H. Anticancer effects of the novel 1alpha, 25-dihydroxyvitamin D3 hybrid analog QW1624F2-2 in human neuroblastoma.. Journal of cellular biochemistry. Vol 97(1) . 2006 Jan:198-206.
    • Damodar Reddy C, Guttapalli Asha, Adamson Peter C, Vemuri Mohan C, O'Rourke Donald, Sutton Leslie N, Phillips Peter C. Anticancer effects of fenretinide in human medulloblastoma.. Cancer letters. Vol 231(2) . 2006 Jan:262-9.
    • Gururangan Sridharan, Petros William P, Poussaint Tina Young, Hancock Michael L, Phillips Peter C, Friedman Henry S, Bomgaars Lisa, Blaney Susan M, Kun Larry E, Boyett James M. Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004).. Clinical cancer research : an official journal of the American Association for Cancer Research. Vol 12(5) . 2006 Mar:1540-6.
    • Kaplan Robert H, Phillips Patrick C. Ecological and developmental context of natural selection: maternal effects and thermally induced plasticity in the frog Bombina orientalis.. Evolution; international journal of organic evolution. Vol 60(1) . 2006 Jan:142-56.
    • Armstrong G T, Localio A R, Feygin T, Bilaniuk L, Phillips P C, Fisher M J, Strom B L, Zimmerman R. Defining optic nerve tortuosity.. AJNR. American journal of neuroradiology. Vol 28(4) . 2007 Apr:666-71.
    • D'cunja J, Shalaby T, Rivera P, von Büren A, Patti R, Heppner F L, Arcaro A, Rorke-Adams L B, Phillips P C, Grotzer M A. Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells.. European journal of cancer (Oxford, England : 1990). Vol 43(10) . 2007 Jul:1581-9.
    • Shu Hui-Kuo G, Sall Walter F, Maity Amit, Tochner Zelig A, Janss Anna J, Belasco Jean B, Rorke-Adams Lucy B, Phillips Peter C, Sutton Leslie N, Fisher Michael J. Childhood intracranial ependymoma: twenty-year experience from a single institution.. Cancer. Vol 110(2) . 2007 Jul:432-41.
    • Poussaint T Young, Phillips P C, Vajapeyam S, Fahey F H, Robertson R L, Osganian S, Ramamurthy U, Mulkern R V, Treves S T, Boyett J M, Kun L E. The Neuroimaging Center of the Pediatric Brain Tumor Consortium-collaborative neuroimaging in pediatric brain tumor research: a work in progress.. AJNR. American journal of neuroradiology. Vol 28(4) . 2007 Apr:603-7.
    • Gururangan Sridharan, Fisher Michael J, Allen Jeffrey C, Herndon James E, Quinn Jennifer A, Reardon David A, Vredenburgh James J, Desjardins Annick, Phillips Peter C, Watral Melody A, Krauser Jeanne M, Friedman Allan H, Friedman Henry S. Temozolomide in children with progressive low-grade glioma.. Neuro-oncology. Vol 9(2) . 2007 Apr:161-8.
    • Manoel Diogo, Carvalho Sara, Phillips Patrick C, Teotónio Henrique. Selection against males in Caenorhabditis elegans under two mutational treatments.. Proceedings. Biological sciences / The Royal Society. Vol 274(1608) . 2007 Feb:417-24.
    • Cresko William A, McGuigan Katrina L, Phillips Patrick C, Postlethwait John H. Studies of threespine stickleback developmental evolution: progress and promise.. Genetica. Vol 129(1) . 2007 Jan:105-26.
    • Phillips Patrick C. What maintains genetic variation in natural populations? A commentary on 'The maintenance of genetic variability by mutation in a polygenic character with linked loci' by Russell Lande.. Genetical research. Vol 89(5-6) . 2007 Dec:371-2.
    • Anderson Jennifer L, Albergotti Lori, Proulx Stephen, Peden Colin, Huey Raymond B, Phillips Patrick C. Thermal preference of Caenorhabditis elegans: a null model and empirical tests.. The Journal of experimental biology. Vol 210(Pt 17) . 2007 Sep:3107-16.
    • Phillips Patrick C. Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems.. Nature reviews. Genetics. Vol 9(11) . 2008 Nov:855-67.
    • Kammenga Jan E, Phillips Patrick C, De Bono Mario, Doroszuk Agnieszka. Beyond induced mutants: using worms to study natural variation in genetic pathways.. Trends in genetics : TIG. Vol 24(4) . 2008 Apr:178-85.
    • Gururangan Sridharan, Turner Christopher D, Stewart Clinton F, O'Shaughnessy Melinda, Kocak Mehmet, Poussaint Tina Young, Phillips Peter C, Goldman Stewart, Packer Roger, Pollack Ian F, Blaney Susan M, Karsten Verena, Gerson Stanton L, Boyett James M, Friedman Henry S, Kun Larry E. Phase I trial of VNP40101M (Cloretazine) in children with recurrent brain tumors: a pediatric brain tumor consortium study.. Clinical cancer research : an official journal of the American Association for Cancer Research. Vol 14(4) . 2008 Feb:1124-30.
    • Phillips Patrick C. Evolutionary genetics: who shouldn't be your daddy.. Nature. Vol 451(7179) . 2008 Feb:640-1.
    • Fisher Michael J, Basu Sandip, Dombi Eva, Yu Jian Q, Widemann Brigitte C, Pollock Avrum N, Cnaan Avital, Zhuang Hongming, Phillips Peter C, Alavi Abass. The role of [18F]-fluorodeoxyglucose positron emission tomography in predicting plexiform neurofibroma progression.. Journal of neuro-oncology. Vol 87(2) . 2008 Apr:165-71.
    • Baltrus David A, Guillemin Karen, Phillips Patrick C. Natural transformation increases the rate of adaptation in the human pathogen Helicobacter pylori.. Evolution; international journal of organic evolution. Vol 62(1) . 2008 Jan:39-49.
    • Jovelin Richard, Dunham Joseph P, Sung Frances S, Phillips Patrick C. High nucleotide divergence in developmental regulatory genes contrasts with the structural elements of olfactory pathways in caenorhabditis.. Genetics. Vol 181(4) . 2009 Apr:1387-97.
    • Chandler C H, Phillips P C, Janzen F J. The evolution of sex-determining mechanisms: lessons from temperature-sensitive mutations in sex determination genes in Caenorhabditis elegans.. Journal of evolutionary biology. Vol 22(1) . 2009 Jan:192-200.
    • Morran Levi T, Parmenter Michelle D, Phillips Patrick C. Mutation load and rapid adaptation favour outcrossing over self-fertilization.. Nature. Vol 462(7271) . 2009 Nov:350-2.
    • Jovelin Richard, Phillips Patrick C. Evolutionary rates and centrality in the yeast gene regulatory network.. Genome biology. Vol 10(4) . 2009:R35.
    • Morran Levi T, Cappy Brian J, Anderson Jennifer L, Phillips Patrick C. Sexual partners for the stressed: facultative outcrossing in the self-fertilizing nematode Caenorhabditis elegans.. Evolution; international journal of organic evolution. Vol 63(6) . 2009 Jun:1473-82.
    • Denver Dee R, Howe Dana K, Wilhelm Larry J, Palmer Catherine A, Anderson Jennifer L, Stein Kevin C, Phillips Patrick C, Estes Suzanne. Selective sweeps and parallel mutation in the adaptive recovery from deleterious mutation in Caenorhabditis elegans.. Genome research. Vol 20(12) . 2010 Dec:1663-71.
    • Barker Brittany S, Phillips Patrick C, Arnold Stevan J. A test of the conjecture that G-matrices are more stable than B-matrices.. Evolution; international journal of organic evolution. Vol 64(9) . 2010 Sep:2601-13.
    • Dowell Robin D, Ryan Owen, Jansen An, Cheung Doris, Agarwala Sudeep, Danford Timothy, Bernstein Douglas A, Rolfe P Alexander, Heisler Lawrence E, Chin Brian, Nislow Corey, Giaever Guri, Phillips Patrick C, Fink Gerald R, Gifford David K, Boone Charles. Genotype to phenotype: a complex problem.. Science (New York, N.Y.). Vol 328(5977) . 2010 Apr:469.
    • Anderson Jennifer L, Morran Levi T, Phillips Patrick C. Outcrossing and the maintenance of males within C. elegans populations.. The Journal of heredity. Vol 101 Suppl 1. 2010 Mar-Apr:S62-74.
    • Gaertner Bryn E, Phillips Patrick C. Caenorhabditis elegans as a platform for molecular quantitative genetics and the systems biology of natural variation.. Genetics research. Vol 92(5-6) . 2010 Dec:331-48.
    • Morran Levi T, Ohdera Aki H, Phillips Patrick C. Purging deleterious mutations under self fertilization: paradoxical recovery in fitness with increasing mutation rate in Caenorhabditis elegans.. PloS one. Vol 5(12) . 2010:e14473.
    • Hohenlohe Paul A, Phillips Patrick C, Cresko William A. USING POPULATION GENOMICS TO DETECT SELECTION IN NATURAL POPULATIONS: KEY CONCEPTS AND METHODOLOGICAL CONSIDERATIONS.. International journal of plant sciences. Vol 171(9) . 2010 Nov:1059-1071.
    • McCormick Kathryn E, Gaertner Bryn E, Sottile Matthew, Phillips Patrick C, Lockery Shawn R. Microfluidic devices for analysis of spatial orientation behaviors in semi-restrained Caenorhabditis elegans.. PloS one. Vol 6(10) . 2011:e25710.
    • Anderson Jennifer L, Reynolds Rose M, Morran Levi T, Tolman-Thompson Julie, Phillips Patrick C. Experimental evolution reveals antagonistic pleiotropy in reproductive timing but not life span in Caenorhabditis elegans.. The journals of gerontology. Series A, Biological sciences and medical sciences. Vol 66(12) . 2011 Dec:1300-8.
    • Jovelin Richard, Phillips Patrick C. Expression level drives the pattern of selective constraints along the insulin/Tor signal transduction pathway in Caenorhabditis.. Genome biology and evolution. Vol 3. 2011:715-22.
    • Estes Suzanne, Phillips Patrick C, Denver Dee R. Fitness recovery and compensatory evolution in natural mutant lines of C. elegans.. Evolution; international journal of organic evolution. Vol 65(8) . 2011 Aug:2335-44.
    • Anderson Jennifer L, Albergotti Lori, Ellebracht Barbara, Huey Raymond B, Phillips Patrick C. Does thermoregulatory behavior maximize reproductive fitness of natural isolates of Caenorhabditis elegans?. BMC evolutionary biology. Vol 11. 2011:157.
    • Mendenhall Alexander R, Wu Deqing, Park Sang-Kyu, Cypser James R, Tedesco Patricia M, Link Christopher D, Phillips Patrick C, Johnson Thomas E. Genetic dissection of late-life fertility in Caenorhabditis elegans.. The journals of gerontology. Series A, Biological sciences and medical sciences. Vol 66(8) . 2011 Aug:842-54.
    • Avery Robert A, Liu Grant T, Fisher Michael J, Quinn Graham E, Belasco Jean B, Phillips Peter C, Maguire Maureen G, Balcer Laura J. Retinal nerve fiber layer thickness in children with optic pathway gliomas.. American journal of ophthalmology. Vol 151(3) . 2011 Mar:542-9.e2.
    • Minturn Jane E, Janss Anna J, Fisher Paul G, Allen Jeffrey C, Patti Ratnakar, Phillips Peter C, Belasco Jean B. A phase II study of metronomic oral topotecan for recurrent childhood brain tumors.. Pediatric blood & cancer. Vol 56(1) . 2011 Jan:39-44.
    • Parsons D Williams, Li Meng, Zhang Xiaosong, Jones Siân, Leary Rebecca J, Lin Jimmy Cheng-Ho, Boca Simina M, Carter Hannah, Samayoa Josue, Bettegowda Chetan, Gallia Gary L, Jallo George I, Binder Zev A, Nikolsky Yuri, Hartigan James, Smith Doug R, Gerhard Daniela S, Fults Daniel W, VandenBerg Scott, Berger Mitchel S, Marie Suely Kazue Nagahashi, Shinjo Sueli Mieko Oba, Clara Carlos, Phillips Peter C, Minturn Jane E, Biegel Jaclyn A, Judkins Alexander R, Resnick Adam C, Storm Phillip B, Curran Tom, He Yiping, Rasheed B Ahmed, Friedman Henry S, Keir Stephen T, McLendon Roger, Northcott Paul A, Taylor Michael D, Burger Peter C, Riggins Gregory J, Karchin Rachel, Parmigiani Giovanni, Bigner Darell D, Yan Hai, Papadopoulos Nick, Vogelstein Bert, Kinzler Kenneth W, Velculescu Victor E. The genetic landscape of the childhood cancer medulloblastoma.. Science (New York, N.Y.). Vol 331(6016) . 2011 Jan:435-9.
    • Gaertner Bryn E, Parmenter Michelle D, Rockman Matthew V, Kruglyak Leonid, Phillips Patrick C. More than the sum of its parts: a complex epistatic network underlies natural variation in thermal preference behavior in Caenorhabditis elegans.. Genetics. Vol 192(4) . 2012 Dec:1533-42.
    • Fierst Janna L, Phillips Patrick C. Variance in epistasis links gene regulation and evolutionary rate in the yeast genetic interaction network.. Genome biology and evolution. Vol 4(11) . 2012:1080-7.
    • Campen Cynthia J, Kranick Sarah M, Kasner Scott E, Kessler Sudha K, Zimmerman Robert A, Lustig Robert, Phillips Peter C, Storm Phillip B, Smith Sabrina E, Ichord Rebecca, Fisher Michael J. Cranial irradiation increases risk of stroke in pediatric brain tumor survivors.. Stroke; a journal of cerebral circulation. Vol 43(11) . 2012 Nov:3035-40.
    • Wu Deqing, Tedesco Patricia M, Phillips Patrick C, Johnson Thomas E. Fertility/longevity trade-offs under limiting-male conditions in mating populations of Caenorhabditis elegans.. Experimental gerontology. Vol 47(10) . 2012 Oct:759-63.
    • Armstrong Carol L, Shera David M, Lustig Robert A, Phillips Peter C. Phase measurement of cognitive impairment specific to radiotherapy.. International journal of radiation oncology, biology, physics. Vol 83(3) . 2012 Jul:e319-24.
    • Phillips Patrick C. Self-fertilization sweeps up variation in the worm genome.. Nature genetics. Vol 44(3) . 2012 Mar:237-8.
    • Kimmel Charles B, Cresko William A, Phillips Patrick C, Ullmann Bonnie, Currey Mark, von Hippel Frank, Kristjánsson Bjarni K, Gelmond Ofer, McGuigan Katrina. Independent axes of genetic variation and parallel evolutionary divergence of opercle bone shape in threespine stickleback.. Evolution; international journal of organic evolution. Vol 66(2) . 2012 Feb:419-34.
    • Chandler Christopher H, Chadderdon Genna E, Phillips Patrick C, Dworkin Ian, Janzen Fredric J. Experimental evolution of the Caenorhabditis elegans sex determination pathway.. Evolution; international journal of organic evolution. Vol 66(1) . 2012 Jan:82-93.
    • Kranick Sarah M, Campen Cynthia J, Kasner Scott E, Kessler Sudha K, Zimmerman Robert A, Lustig Robert A, Phillips Peter C, Beslow Lauren A, Ichord Rebecca, Fisher Michael J. Headache as a risk factor for neurovascular events in pediatric brain tumor patients.. Neurology. Vol 80(16) . 2013 Apr:1452-6.
  • Retinal nerve fiber layer thickness in children with optic pathway gliomas. Avery RA, Liu GT, Fisher MJ, Quinn GE, Belasco JB, Phillips PC, Maguire MG, Balcer LJ. Am J Ophthalmol. 2011 Mar;151(3):542-549.e2.
  • USING POPULATION GENOMICS TO DETECT SELECTION IN NATURAL POPULATIONS: KEY CONCEPTS AND METHODOLOGICAL CONSIDERATIONS. Hohenlohe PA, Phillips PC, Cresko WA. Int J Plant Sci. 2010 Nov 1;171(9):1059-1071.
  • Purging deleterious mutations under self fertilization: paradoxical recovery in fitness with increasing mutation rate in Caenorhabditis elegans. Morran LT, Ohdera AH, Phillips PC. PLoS One. 2010 Dec 31;5(12).
  • The genetic landscape of the childhood cancer medulloblastoma. Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE. Science. 2011 Jan 28;331(6016):435-9.
  • A phase II study of metronomic oral topotecan for recurrent childhood brain tumors. Minturn JE, Janss AJ, Fisher PG, Allen JC, Patti R, Phillips PC, Belasco JB. Pediatr Blood Cancer. 2011 Jan;56(1):39-44.
  • Selective sweeps and parallel mutation in the adaptive recovery from deleterious mutation in Caenorhabditis elegans. Denver DR, Howe DK, Wilhelm LJ, Palmer CA, Anderson JL, Stein KC, Phillips PC, Estes S. Genome Res. 2010 Dec;20(12):1663-71.
  • A test of the conjecture that G-matrices are more stable than B-matrices. Barker BS, Phillips PC, Arnold SJ. Evolution. 2010 Sep;64(9):2601-13.
  • Genotype to phenotype: a complex problem. Dowell RD, Ryan O, Jansen A, Cheung D, Agarwala S, Danford T, Bernstein DA, Rolfe PA, Heisler LE, Chin B, Nislow C, Giaever G, Phillips PC, Fink GR, Gifford DK, Boone C. Science. 2010 Apr 23;328(5977):469.
  • Outcrossing and the maintenance of males within C. elegans populations. Anderson JL, Morran LT, Phillips PC. J Hered. 2010 Mar-Apr;101 Suppl 1:S62-74.
  • Mutation load and rapid adaptation favour outcrossing over self-fertilization. Morran LT, Parmenter MD, Phillips PC. Nature. 2009 Nov 19;462(7271):350-2.
  • Evolutionary rates and centrality in the yeast gene regulatory network. Jovelin R, Phillips PC. Genome Biol. 2009;10(4):R35.
  • Sexual partners for the stressed: facultative outcrossing in the self-fertilizing nematode Caenorhabditis elegans. Morran LT, Cappy BJ, Anderson JL, Phillips PC. Evolution. 2009 Jun;63(6):1473-82.
  • The evolution of sex-determining mechanisms: lessons from temperature-sensitive mutations in sex determination genes in Caenorhabditis elegans. Chandler CH, Phillips PC, Janzen FJ. J Evol Biol. 2009 Jan;22(1):192-200.
  • High nucleotide divergence in developmental regulatory genes contrasts with the structural elements of olfactory pathways in caenorhabditis. Jovelin R, Dunham JP, Sung FS, Phillips PC. Genetics. 2009 Apr;181(4):1387-97.
  • What maintains genetic variation in natural populations? A commentary on 'The maintenance of genetic variability by mutation in a polygenic character with linked loci' by Russell Lande. Phillips PC. Genet Res. 2007 Dec;89(5-6):371-2.
  • Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems. Phillips PC. Nat Rev Genet. 2008 Nov;9(11):855-67.
  • Beyond induced mutants: using worms to study natural variation in genetic pathways. Kammenga JE, Phillips PC, De Bono M, Doroszuk A. Trends Genet. 2008 Apr;24(4):178-85. Epub 2008 Mar 5.
  • Phase I trial of VNP40101M (Cloretazine) in children with recurrent brain tumors: a pediatric brain tumor consortium study. Gururangan S, Turner CD, Stewart CF, O'Shaughnessy M, Kocak M, Poussaint TY, Phillips PC, Goldman S, Packer R, Pollack IF, Blaney SM, Karsten V, Gerson SL, Boyett JM, Friedman HS, Kun LE. Clin Cancer Res. 2008 Feb 15;14(4):1124-30.
  • Evolutionary genetics: who shouldn't be your daddy. Phillips PC. Nature. 2008 Feb 7;451(7179):640-1.
  • The role of [18F]-fluorodeoxyglucose positron emission tomography in predicting plexiform neurofibroma progression. Fisher MJ, Basu S, Dombi E, Yu JQ, Widemann BC, Pollock AN, Cnaan A, Zhuang H, Phillips PC, Alavi A. J Neurooncol. 2008 Apr;87(2):165-71. Epub 2007 Dec 11.