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Developmental Therapeutics
Peter C. Phillips, MD
Peter C. Phillips, MD
Developmental Therapeutics
Clinical outcome in children with recurrent neuroblastoma treated with ABT-751 and effect of ABT-751 on proliferation of neuroblastoma cell lines and on tubulin polymerization in vitro
Clinical trial design for target-based therapy
Extracellular fluid concentrations of cisplatin, carboplatin, and oxaliplatin in brain, muscle, and blood measured using microdialysis in nonhuman primates
Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome
Pediatric phase I trial design using maximum target inhibition as the primary endpoint
Pharmacokinetics of orally administered ABT-751 in children with neuroblastoma and other solid tumors
Phase I trial and pharmacokinetic study of ixabepilone administered daily for 5 days in children and adolescents with refractory solid tumors
Plasma and CNS pharmacokinetics of O(4)-benzylfolic acid (O (4)BF) and metabolite in a non-human primate model
Randomized trial and pharmacokinetic study of pegfilgrastim versus filgrastim after dose-intensive chemotherapy in young adults and children with sarcomas